Biosafety Cabinet Class III

The Class III biological safety cabinet provides an absolute level of safety, which cannot be attained with Class I and Class II cabinets. All Class III cabinets are usually made of welded metal construction and are designed to be gas tight and work is performed through glove ports in the front of the cabinet. During routine operation, negative pressure relative to the ambient environment is maintained within the cabinet which provides an additional fail-safe mechanism in case physical containment is compromised.

On all Class III cabinets, a supply of HEPA filtered air provides product protection and prevents cross contamination of samples while exhaust air is HEPA-filtered and incinerated. Materials are transferred into the cabinet using a pass-through unit installed at the side of the work area.

Class III cabinets usually exhaust air back to the laboratory; however, air may also be exhausted via a dedicated ductwork system to the external environment. When a dedicated ductwork system is employed, they are also suitable for work employing toxic chemicals as an adjunct to microbiological processes